Workshops

DATE

25 June 2020 (See registration fees for cost)

FORMAT OF THE PROGRAM

Short updates in form of presentations, interactive case-based studies followed by a panel discussion and Q&A.

PROPOSED AGENDA WITH SPEAKER SUGGESTIONS

TimePresenterDuration
Workshop - ChairsBernardo Rapoport
Mario Lacouture
Basic mechanisms Bernardo Rapoport
Car T-cell therapy: Overview and management of toxicitiesKevin J. Curran (TBC)
Case study - immune related adverse events (irAEs):
  • Endocrine
Tim Cooksley
Case study - immune related adverse events (irAEs):
  • Dermatological
Mario Lacouture
Case study - immune related adverse events (irAEs):
  • GI
Bernardo Rapoport
Case study - immune related adverse events (irAEs):
  • Multiple and refractory toxicities
Michael Postow (TBC)
Case study - immune related adverse events (irAEs):
  • Effective patient - Healthcare provider communication
Pamela Ginex
Oncology Nursing Society

PANEL DISCUSSION

EDUCATIONAL OBJECTIVES

Immuno-oncology is a rapidly evolving field.  As these agents enter the community clinical care setting it is important to be aware of specific immunotherapy-related adverse effects and how to manage them.

The overarching objective of the workshop is to keep healthcare professionals up-to-date regarding the assessment and management of immune related adverse events associated with anti CTL4 and anti PD1/PDL1 antibodies and other immune checkpoint inhibitors, with special emphasis on irAE, irAE emergencies and CAR T-cell therapy.  The workshop will also give participants a forum to discuss case studies and debate management.

 

This workshop is intended to:

  1. Provide an update on the basic mechanism of action of immune checkpoint inhibitors (anti CTL4, anti PD1/PDL1 antibodies, combinations with chemotherapy, radiotherapy, targeted therapies and anti-angiogenenic agents).
  2.  Give an overview of the current and potential use of these agent.
  3.  Provide an overview of the main immune-related adverse events and include recommendations for their management to optimize patient health.
  4. Analyze new clinical trials for incorporation in clinical application.
  5. Educate healthcare providers and patients to be constantly vigilant and connect seemingly unrelated effects with immunotherapy, especially with the delayed onset of many irAE’s and highlighting the importance of effective patient healthcare provider communication.

DATE

25 June 2020 (See registration fees for cost)

FORMAT OF THE PROGRAM

Lectures, Group discussion, Interactive workshop.

PROPOSED AGENDA WITH SPEAKER SUGGESTIONS

TimePresenterDuration
08:00 - 08:10 Introduction and aims of the workshop - Study chairs 10 mins
08:10 - 09:25 Oral healthcare in older adults with cancer:
08:10 - 09:25
  • Oncologists’ view
Dr. Christopher Steer25 mins
08:10 - 09:25
  • Dietitians’ view
Prof Liz Isenring25 mins
08:10 - 09:25
  • Dentists’ view
Kivanc Bektas Kayhan25 mins
09:30 - 10:30 Practical aspects of oral health and nutrition assessment – Interactive session What tools are needed? How do you describe oral pathology? Practical nutritional interventions and dietary modifications in older adults. How do we improve nutritional intake and quality of life? Moderated by:

Kivanc Kayhan
Suzanne Carlisle
Liz Isenring
(and junior researcher TBA)
60 mins
10:30 - 11:00 Group discussion What oral assessment should be part of the geriatric assessment in older adults with cancer. Future collaboration opportunities. Discussion about manuscript preparation. 30 mins

EDUCATIONAL OBJECTIVES

Investigation of the key issues in oral care in older adults with cancer

  1. From the oncologist point of view:
    1. What are the problems older patients face in relation to orodental health and nutrition?
    2. Geriatric assessment as a supportive care strategy in older adults with cancer – What do oncologists do now to assess oral health and nutrition? How does this impact treatment?
    3. What are the risks you have in geriatric oncology patients regarding inadequate nutrition and orodental problems?
  2. Dietitian’s perspective:
    1. Nutritional issues in older patients with cancer – the role of the dietitian in the
      multidisciplinary team.
    2. How do dietitians assess nutrition and oral intake in older adults? Do they screen for oral health.
    3. Nutritional interventions and dietary modifications in older adults with cancer.
  3. From the dentist’s point of view:
    1. What are the orodental problems seen in older adults with cancer?
    2. What are the impacts of poor oral health in older adults with cancer?
    3. How do dentists assess oral health?
    4. What interventions are available to prevent and manage oral healthcare issues in older adults?
  4.  How can oncologists and dietitians assess oral health in older adults with cancer? What oral healthcare assessment should be part of the comprehensive geriatric assessment?

DATE

25 June 2020 (See registration fees for cost)

FORMAT OF THE PROGRAM

  1. Abstract submission-based oral presentations (5)
  2. Invited presentations (3)
  3. Interactive panel using role-play
    1. Scenarios will be presented.
    2. Volunteers will role-play.

Expert panelists and audience will comment.

PROPOSED AGENDA WITH SPEAKER SUGGESTIONS

Invited talks – topics related to the theme:

  1. Pathogenesis of GI-mucositis induced by immune-therapy – Dr. Pernot, France.
  2. Mucositis in the era of heavy ion-beam RT – Dr. Orlandi, Italy.
  3. New manifestations of oral mucositis post proton-beam RT – Drs. Estilo and Owosho, USA.
  4. Appliances for the management of oral mucositis – Dr. Yarom, Israel.
  5. Future directions in research and care for mucositis – Dr. Sonis, USA.
TimePresenterDuration
Opening Dr. Elad
Abstract based presentations 4 presenters40 mins
Pathogenesis of GI-mucositis induced by immune-therapy Dr. Pernot 20 mins

BREAK

[20 mins]
Appliances for MucositisDr. Yarom20 mins
Principles of heavy - beam radiotherapyDr. Orlandi20 mins
New manifestations of oral mucositis post proton - beam radiotherapy Dr. Owosho
Dr. Estilo
10 mins
Case-based panel discussion *
  • Present scenario
  • Role-play (patient/clinician)
  • Audience comment
  • Panel discuss
Panelist:
  • JD/ethics expert
  • Medical oncologist
  • Nurse
  • Dental oncologist
Dr. Elad
Dr. Bossi
Dr. Cheng
Dr. Estilo
Dr. Shaw
30 mins
Future directions Dr. Sonis20 mins

Total

3 hours

EDUCATIONAL OBJECTIVES

The overall goal of the workshop is to bring together basic, translational and clinical researchers in an informal setting to advance the understanding of mucositis.

The specific objectives of the workshop are to:

  1. Present the latest state of the science in mucositis research.
  2. Provide an opportunity for young investigators to present their work to an expert audience for
    specialized feedback and research advice.
  3. Facilitate exchange of knowledge between experts and young researchers from all over the world, including participation in role play scenarios.
  4. Provide an opportunity for face to face discussions regarding collaborative research and development of international research networks.
  5. Develop links with multidisciplinary teams to pursue new research and funding opportunities.